St John's Wort Research Today is a free monthly online journal that collates and summarizes the latest research about St John's Wort, including details on depression, anxiety, side-effects, dosage, benefits.

Hyperforin: more than an antidepressant bioactive compound?

Medina MA, Martínez-Poveda B, Amores-Sánchez MI, Quesada AR

Department of Molecular Biology and Biochemistry, Faculty of Sciences, University of Málaga, E-29071 Málaga, Spain. medina@uma.es

Hyperforin is a lipophilic compound that is present in great amounts in St. John's wort and that has been described as the main responsible for the antidepressant effects of this medicinal plant. In the last few years, evidence has accumulated pointing to other different effects of hyperforin with potential pharmacological interest. They include other neurological effects, effects on inflammation, as well as antibacterial, antitumoral and antiangiogenic effects.

Published 26 May 2006 in Life Sci, 79(2): 105-11.
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